Organ-saving device wins top innovation award

Galya Dimitrova & Jordan Brooks
BBC News, Oxford
OrganOx The OrganOx team at the Royal Academy of Engineering award ceremony, with Prof Constantin Coussios in the middle, holding the award. The team is smiling for the camera. OrganOx
Prof Constantin Coussios, who is seen holding the award, has worked for 17 years to bring the technology to fruition

The team behind a pioneering device that keeps human organs alive outside the body has earned a top engineering prize.

The device manufactured by Oxford-based OrganOx won this year's MacRobert Award, which is run by the Royal Academy of Engineering, on Tuesday.

OrganOx was founded in 2009 by biomedical engineer Prof Constantin Coussios and transplant surgeon Prof Peter Friend.

Their device mimics the human body by pumping a blood-like fluid through organs at normal body temperature, supplying oxygen and nutrients.

OrganOx A person in blue latex gloves working on a liver hooked onto the OrganOx machine.OrganOx
The technology creates an environment where the organ can function outside the body

This allows organs - such as livers and kidneys - to remain functional for over 24 hours, producing bile and urine, and even repairing themselves.

"The fact that there are 6,500 people alive today because of those efforts is what this award recognises," Prof Coussios said.

A major US transplant centre reported a drop in median liver transplant wait times from 82 to 14 days, and a reduction in waiting list mortality from 18% to 6%.

Recently, the team successfully transplanted 36 kidneys in a first-in-human trial in Oxford.

With over 7,500 people still on the UK transplant waiting list, the technology offers hope.

"Liver and kidney transplantation are in our immediate sights," said Prof Coussios.